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Nottinghamshire Area Prescribing Committee
Joint Formulary
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 Formulary Chapter 2: Cardiovascular system - Full Chapter
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02.11  Expand sub section  Antifibrinolytic drugs and haemostatics
02.11  Expand sub section  Blood-related products
Albutrepenonacog alfa (Idelvion®)
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted
Red
High Cost Medicine

Non pharmacy item, please contact blood bank for details and availability

 
   
Antithrombin III (Kybernin®)
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted
Red
High Cost Medicine

Non pharmacy item please contact blood bank for details and availability.

 
   
Efmoroctocog alfa (Elocta®)
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted
Red
High Cost Medicine
Homecare

Non pharmacy item please contact blood bank for details and availability

 

Available through homecare for NUH patients. Please contact pharmacy medicines homecare team for further information

 
   
Eftrenonacog alfa (Alprolix®)
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted
Red
High Cost Medicine
Homecare

Non pharmacy item, please contact blood bank for details and availability.

 

Available through homecare for NUH patients. Please contact pharmacy medicines homecare team for further information

 
   
Emicizumab (Hemlibra®)
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted
Red
High Cost Medicine
Homecare

Injection

Available at NUH only:

  • Approved in accordance with the Clinical Commissioning Policy for the prophylaxis in people with cogential haemophilia A with factor VIII inhibitors (all ages).
  • Approved in accordance with the Clinical Commissioning Policy for the prophylaxis in people with severe cogential haemophilia A without factor VIII inhibitors (all ages).

Available through homecare for NUH patients.  Please contact pharmacy medicines homecare team for further information.

 
   
Factor Eight Inhibitor Bypassing Fraction (Feiba®)
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted
Red
High Cost Medicine
Homecare

Non pharmacy item, please contact blood bank for details and availability

 

Available through homecare for NUH patients. Please contact pharmacy medicines homecare team for further information

 
   
Factor VIIa (Recombinant), Eptacog alfa (NovoSeven®)
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted
Red
High Cost Medicine
Homecare

Non pharmacy item please contact blood bank for details and availability.

  • At SFH, one dose is stocked in blood bank. In the event of further doses being required (consultant haematologist request only), contact pharmacy (or on call pharmacist out of hours). See memo for further details.
  • Available through homecare for NUH patients. Please contact pharmacy medicines homecare team for further information
 
   
Factor VIII (NovoEight®)
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted
Red
High Cost Medicine

Non pharmacy item, please contact blood bank for details and availability

 

Available through homecare for NUH patients. Please contact pharmacy medicines homecare team for further information

 
   
Factor VIII - Von willebrand factor (Type 8Y®)
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted
Red
High Cost Medicine

Non pharmacy item, please contact blood bank for details and availability

 
   
Factor VIII - Von willebrand factor (Wilate®)
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted
Red
High Cost Medicine

Non pharmacy item, please contact blood bank for details and availability

 
   
Factor VIII + von Willebrand factor (Voncento®)
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted
Red
High Cost Medicine
Homecare

Factor VIII, von willebrand factor - NUH only

Non pharmacy item please contact blood bank for details and availability

Available through homecare for NUH patients. Please contact pharmacy medicines homecare team for further information

 
   
Human Fibrinogen (Riastap®)
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted
Red
High Cost Medicine
Homecare

Non pharmacy item, please contact blood bank for details and availability

Available through homecare for NUH patients. Please contact pharmacy medicines homecare team for further information

 
   
Moroctocog alfa (Refacto®)
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted
Red
High Cost Medicine
Homecare

Non pharmacy item, please contact blood bank for details and availability

 

Available through homecare for NUH patients. Please contact pharmacy medicines homecare team for further information

 
   
Nonacog alfa (BeneFIX®)
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted
Red
High Cost Medicine
Homecare

Non pharmacy item, please contact blood bank for details and availability

 

Available through homecare for NUH patients. Please contact pharmacy medicines homecare team for further information

 
   
Octocog alfa (Advate®)
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted
Red
High Cost Medicine
Homecare

Non pharmacy item, please contact blood bank for details and availability

 

Available through homecare for NUH patients. Please contact pharmacy medicines homecare team for further information

 
   
Octocog alfa (Kogenate®)
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted
Red
High Cost Medicine

Non pharmacy item, please contact blood bank for details and availability

 
   
Protein C Concentrate (Ceprotin®)
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted
Red
High Cost Medicine
Non pharmacy item please contact blood bank for details and availability. 
   
Prothrombin Complex Concentrate  (Octaplex®)
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted
Red
High Cost Medicine

SFH:  Pharmacy to order in for pathology to keep as stock

Non pharmacy item please contact blood bank for details and availability.

 
Link  (SFH) Octaplex administration guide
Link  Manufacturers data sheet (SPC)
   
Simoctocog alfa (Nuwiq®)
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted
Red
High Cost Medicine
Homecare

Recombinant Factor VIII Product - NUH only

Non pharmacy item please contact blood bank for details and availability

Available through homecare for NUH patients. Please contact pharmacy medicines homecare team for further information

 
   
Susoctocog alfa (Obizur®)
Restricted Drug Restricted
Red
High Cost Medicine

Injection

Approved in accordance with the Clinical Commissioning Policy for use in treating bleeding episodes in people with acquired haemophilia A (all ages).

Non pharmacy item, please contact haemophilia unit for details and availability.

 
   
Von willebrand factor (Willfact®)
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted
Red
High Cost Medicine

Non pharmacy item, please contact blood bank for details and availability

 
   
 ....
 Non Formulary Items
Drotrecogin Alfa (Activated)  (Xigris®)

View adult BNF View SPC online View childrens BNF
Non Formulary
Grey
  • Marketing authorisation withdrawn October 2011
  • Link  Link to reviews
     
    Factor IX Fraction, Dried

    View adult BNF View SPC online View childrens BNF
    Non Formulary
    Grey
    High Cost Medicine
     
    Factor VIII Fraction, Dried

    View adult BNF View SPC online View childrens BNF
    Non Formulary
    Grey
    High Cost Medicine
     
    Factor VIII Inhibitor Bypassing Fraction

    View adult BNF View SPC online View childrens BNF
    Non Formulary
    Grey
    High Cost Medicine
     
    Factor XIII Fraction, Dried

    View adult BNF View SPC online View childrens BNF
    Non Formulary
    Grey
    High Cost Medicine
     
    Fresh Frozen Plasma

    View adult BNF View SPC online View childrens BNF
    Non Formulary
    Grey
     
    Human Coagulation Factor X  (Coagadex®)

    View adult BNF View SPC online View childrens BNF
    Non Formulary
    Grey

    Injection

    • Not recommended in the NHS England Clinical Commissioning Policy 
    Link  Clinical Commissioning Policy: Human coagulation factor X for hereditary factor X deficiency (all ages)
     
    Human fibrinogen & thrombin  (Raplixa® )

    View adult BNF View SPC online View childrens BNF
    Non Formulary
    Grey
  • No formal submission (APC May 15)
  •  
      
    Key
    note Notes
    Section Title Section Title (top level)
    Section Title Section Title (sub level)
    First Choice Item First Choice item
    Non Formulary Item Non Formulary section
    Restricted Drug
    Restricted Drug
    Unlicensed Drug
    Unlicensed
    Track Changes
    Display tracking information
    click to search medicines.org.uk
    Link to adult BNF
    click to search medicines.org.uk
    Link to children's BNF
    click to search medicines.org.uk
    Link to SPCs
    SMC
    Scottish Medicines Consortium
    Cytotoxic Drug
    Cytotoxic Drug
    CD
    Controlled Drug
    High Cost Medicine
    High Cost Medicine
    Cancer Drugs Fund
    Cancer Drugs Fund
    NHSE
    NHS England
    Homecare
    Homecare
    CCG
    CCG

    Traffic Light Status Information

    Status Description

    Grey

    Grey / Non-Formulary: Medicines, which the Nottinghamshire APC has actively reviewed and does not recommend for use at present due to limited clinical and/or cost effective data.
    Grey / Non-Formulary (undergoing assessment): Work is ongoing and will be reviewed at a future APC meeting.
    Grey / Non-Formulary (no formal assessment): APC has not formally reviewed this medicine or indication because it had never been requested for formulary inclusion. Often used for drugs new to market.
      

    Red

    Medicines which should normally be prescribed by specialists only. eg hospital only.
    For patients already receiving prescriptions in primary care - continue. No new patients to receive prescriptions in primary care.
      

    Amber 1

    Medicines that should be initiated by a specialist and prescribed by primary care prescribers only under a shared care protocol, once the patient has been stabilised.
    Prior agreement must be obtained by the specialist from the primary care provider before prescribing responsibility is transferred. The shared care protocol must have been agreed by the relevant secondary care trust Drugs and Therapeutics Committee(s) (DTC) and approved by the Nottinghamshire APC.
      

    Amber 2

    Medicines suitable to be prescribed in primary care / general practice after specialist* recommendation or initiation.
    A supporting prescribing guideline may be requested which must have been agreed by the relevant secondary care trust DTCs and approved by the Nottinghamshire APC.
    *Specialist is defined by the APC as a clinician who has undertaken an appropriate formal qualification or recognised training programme within the described area of practice
      

    Amber 3

    Primary care/ non specialist may initiate as per APC guideline.
    The supporting prescribing guideline must have been agreed by the relevant secondary care trust D&TC(s) and approved by the Nottinghamshire APC.
      

    Green

    Medicines suitable for routine use within primary care.
    Can be initiated within primary care within their licensed indication, in accordance with nationally recognised formularies, for example the BNF, BNF for Children, Medicines for Children or Palliative Care Formulary. Primary care prescribers take full responsibility for prescribing.   

    OTC

      

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