| Formulary Chapter 11: Eye - Full Chapter
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| Chapter Links... |
 Calculator tables to work out how many bottles needed |
 Eye drop compliance aids (Moorfields) |
| Order to administer multiple eye drops |
| Details... |
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Miscellaneous |
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Cytotoxics / wound healing modulators |
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Fluorouracil
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 Restricted
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At NUH: Subconjunctival injection 7.5mg in 0.3mL
Specialist use only
Manufactured by Pharmacy Sterile Production Unit (Unlicensed Product)
At SFH: Subconjunctival injection 7.5mg in 0.3mL (Prescribed when 5mg/ 0.2ml is required) or 50mg/1ml prepared by Aseptic dispensing unit (x3169)
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Mitomycin
(eyes)
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Restricted
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Available as:
- Eye drops 0.04%(preservative free) (Multi dose bottles)- NUH only
- Solution for sub-conjunctival use 0.2mg in 1mL
- Solution for sub-conjunctival use 0.4mg in 1mL (and several other concentrations at KMH aseptic unit)
Sub-conjunctival injection manufactured by Pharmacy Sterile Production Unit (Unlicensed Products)
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Link to reviews
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Fibrinolytic drugs |
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Alteplase intravitreal injection
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Restricted
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Intravitreal injection 25microgram in 0.1mL
Opthalmology specialist at NUH use only
Manufactured by Pharmacy Sterile Production Unit (Unlicensed Product) Lower strengths available upon request
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Glues - ocular |
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Immunosuppressants |
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Ciclosporin
(Eye)
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Restricted
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Oily eye drops 2% (Unlicensed Product), formulated in arachis oil. Avoid in peanut allergy
Eye ointment 0.2% (Unlicensed Vetinary Product, Optimmune®)used only as alternative when 2% drops unavailable. Preservative free but contains lanolin
- both specialist use at NUH only
- 2% eye ointment = non-formulary
- 0.05% preservative free = non-formulary
- 0.06% preservative free multidose = non-formulary
- Neoral® for Uveitis
- Ikervis® 0.1% eye drops single use- Subject of NICE TA369
 - see link below for information sheet
- Verkazia® 0.1% eye drops for vernal keratoconjuntivitis licensed for children (over 4years old) and adolecents (not adults) = - see link below for information sheet
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Ciclosporin eye drops information sheet - Ikarvis
Ciclosporin eye drops information sheet - Verkazia
NICE TA369 - Ciclosporin for treating eye disease that has not improved despite treatment with artificial tears
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Methotrexate
(Eye)
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Formulary
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- For use in Uveitis
- Available through homecare for NUH patients. Please contact pharmacy medicines homecare team for further information
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Treatment of burns |
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Potassium Ascorbate (Ascorbic acid)
(eye drops)
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Formulary
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Eye drops 10% (Unlicensed Product)
Available from NUH and SFH Pharmacy.
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Sodium Citrate
(eye drops)
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Formulary
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Eye drops 10.11% (preservative free) (Unlicensed Product)
Used for acid and alkali burns to the cornea
Available from NUH and SFH Pharmacy.
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Visco-elastics |
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Sodium Hyaluronate
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Formulary
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NUH use
Injection 8.5mg in 0.85mL (Haelonid)
Injection 7.7mg in 0.55mL (Healon G.V.)
Injection 1.2% - 0.8mL syringe (Amvisc)
SFH use
Biolon
Haelon 5
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Sodium Hyaluronate with Lidocaine
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Formulary
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Intracameral injection (Visthesia®)
Intracameral injection (Visthesia Light®)
NUH only
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Link to reviews
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Viscoat Viscoelastic
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Formulary
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0.5mL
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Link to reviews
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Other |
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Disodium Edetate 0.37%
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Formulary
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Solution 20mL (preservative free) (Unlicensed Product)
Specialist use only
At SFH, used by ophthalmology in Daycase. Not routinely stocked, but may be ordered in if needed
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Sodium Chloride 5% eye products
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Formulary
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- For the treatment of corneal oedema or recurrent corneal erosion syndrome.
- Eye drops 5% (Benzalkonium and thiomersol preservatives free). [picture]. 3 month expiry. Licensed as a medical device rather than a medicinal product.
- Eye ointment 5% (Unlicensed Product). Alissa is the most cost effective PF to prescribe in primary care. Prescribe as 5g containers as product expires 4 weeks from opening.
- At SFH, send patients to SFH Pharmacy for supplies of unlicensed medicines
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Key |
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Cytotoxic Drug
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Controlled Drug
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High Cost Medicine
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Cancer Drugs Fund
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NHS England |
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Homecare |
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CCG |
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Traffic Light Status Information
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Description |
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Grey / Non-Formulary: Medicines, which the Nottinghamshire APC has actively reviewed and does not recommend for use at present due to limited clinical and/or cost effective data.
Grey / Non-Formulary (undergoing assessment): Work is ongoing and will be reviewed at a future APC meeting.
Grey / Non-Formulary (no formal assessment): APC has not formally reviewed this medicine or indication because it had never been requested for formulary inclusion. Often used for drugs new to market.
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Medicines which should normally be prescribed by specialists only. eg hospital only.
For patients already receiving prescriptions in primary care - continue. No new patients to receive prescriptions in primary care.
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Medicines that should be initiated by a specialist and prescribed by primary care prescribers only under a shared care protocol, once the patient has been stabilised.
Prior agreement must be obtained by the specialist from the primary care provider before prescribing responsibility is transferred. The shared care protocol must have been agreed by the relevant secondary care trust Drugs and Therapeutics Committee(s) (DTC) and approved by the Nottinghamshire APC.
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Medicines suitable to be prescribed in primary care / general practice after specialist* recommendation or initiation.
A supporting prescribing guideline may be requested which must have been agreed by the relevant secondary care trust DTCs and approved by the Nottinghamshire APC.
*Specialist is defined by the APC as a clinician who has undertaken an appropriate formal qualification or recognised training programme within the described area of practice
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Primary care/ non specialist may initiate as per APC guideline.
The supporting prescribing guideline must have been agreed by the relevant secondary care trust D&TC(s) and approved by the Nottinghamshire APC.
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Medicines suitable for routine use within primary care.
Can be initiated within primary care within their licensed indication, in accordance with nationally recognised formularies, for example the BNF, BNF for Children, Medicines for Children or Palliative Care Formulary. Primary care prescribers take full responsibility for prescribing. |
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