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Nottinghamshire Area Prescribing Committee
Joint Formulary
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 Formulary Chapter 11: Eye - Full Chapter
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11.06  Expand sub section  Treatment of glaucoma
11.06  Expand sub section  Beta-blockers
11.06  Expand sub section  Prostaglandin analogues
Latanoprost
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First Choice
Amber 2

Eye drops 0.005%

  • Preserved latanoprost is generic and now first choice.
  • Preservative free (Monopost®) available for patients who require a preservative free prostaglandin (in unequivocal preservative toxicity / allergy cases).
 
Travoprost (Travatan®)
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Formulary
Amber 2

Eye drops 0.004%

  • Amber 2 - specialist recommendation for the treatment of glaucoma
 
Link  Price comparison graph - all glaucoma treatments
Link  UKMI Q&A: Switching between travoprost and generic latanoprost eye drops
   
Bimatoprost
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Formulary
Amber 2

Eye drops 0.01%, 0.03%.

  • Amber 2 - specialist recommendation for the treatment of glaucoma
  • The 0.01% formulation contains a different concentration of excipients to the 0.03% resulting in greater absorption of the active drug into the eye. Thus the 0.01% formulation is considered to be comparable in IOP-lowering efficacy to the 0.03% formulation. The 0.01% may be associated with a higher risk of preservative- related reactions due to a higher preservative load.
  • Latanoprost preferred
  • Preservative free 0.3% (Lumigan® UDVs or Eyreida® bottles) are Grey Traffic Light (no formal assessment). Use latanoprost PF UDVs instead.
 
Link  Link to reviews
Link  Price comparison graph - all glaucoma treatments
   
Latanoprost with Timolol
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Formulary
Amber 2
  • Prescribe generically (£5.50pm).
  • Xalacom® brand is Non-formulary (£14pm)
  • For preservative free use Fixapost ® UDVs (£13.50)
 
Link  Price comparison graph - all glaucoma treatments
   
Bimatoprost with Timolol
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Formulary
Amber 2

Eye Drops (£14pm), Preservative free UDVs (£18pm)

  • Amber 2 - specialist recommendation for the treatment of glaucoma.
 
Link  Link to reviews
Link  Price comparison graph - all glaucoma treatments
   
Travoprost with Timolol (DuoTrav®)
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Formulary
Amber 2

Travoprost with Timolol Eye Drops (£14pm)

  • Amber 2 - specialist recommendation
  • Latanoprost and timolol preferred (£5.50)
 
Link  Price comparison graph - all glaucoma treatments
   
11.06  Expand sub section  Sympathomimetics
11.06  Expand sub section  Carbonic anhydrase inhibitors and systemic drugs to top
11.06  Expand sub section  Miotics
 ....
 Non Formulary Items
Tafluprost (Preservative Free) 15micrograms/ml  (Saflutan®)

View adult BNF View SPC online View childrens BNF
Non Formulary
Grey
Eye drops (single dose container)
  • Latanoprost preservative free (Monopost®) is now the preservative free prostaglandin analogue of choice as it is more cost effective.
  • Link  Price comparison graph - all glaucoma treatments
     
    Tafluprost and Timolol  (Taptiqom®)

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    Non Formulary
    Grey
  • Fixapost (latanoprost with timolol) is preferred preservative free option. (APC Mar19)
  • Link  Price comparison graph - all glaucoma treatments
     
      
    Key
    note Notes
    Section Title Section Title (top level)
    Section Title Section Title (sub level)
    First Choice Item First Choice item
    Non Formulary Item Non Formulary section
    Restricted Drug
    Restricted Drug
    Unlicensed Drug
    Unlicensed
    Track Changes
    Display tracking information
    click to search medicines.org.uk
    Link to adult BNF
    click to search medicines.org.uk
    Link to children's BNF
    click to search medicines.org.uk
    Link to SPCs
    SMC
    Scottish Medicines Consortium
    Cytotoxic Drug
    Cytotoxic Drug
    CD
    Controlled Drug
    High Cost Medicine
    High Cost Medicine
    Cancer Drugs Fund
    Cancer Drugs Fund
    NHSE
    NHS England
    Homecare
    Homecare
    CCG
    CCG

    Traffic Light Status Information

    Status Description

    Grey

    Grey / Non-Formulary: Medicines, which the Nottinghamshire APC has actively reviewed and does not recommend for use at present due to limited clinical and/or cost effective data.
    Grey / Non-Formulary (undergoing assessment): Work is ongoing and will be reviewed at a future APC meeting.
    Grey / Non-Formulary (no formal assessment): APC has not formally reviewed this medicine or indication because it had never been requested for formulary inclusion. Often used for drugs new to market.
      

    Red

    Medicines which should normally be prescribed by specialists only. eg hospital only.
    For patients already receiving prescriptions in primary care - continue. No new patients to receive prescriptions in primary care.
      

    Amber 1

    Medicines that should be initiated by a specialist and prescribed by primary care prescribers only under a shared care protocol, once the patient has been stabilised.
    Prior agreement must be obtained by the specialist from the primary care provider before prescribing responsibility is transferred. The shared care protocol must have been agreed by the relevant secondary care trust Drugs and Therapeutics Committee(s) (DTC) and approved by the Nottinghamshire APC.
      

    Amber 2

    Medicines suitable to be prescribed in primary care / general practice after specialist* recommendation or initiation.
    A supporting prescribing guideline may be requested which must have been agreed by the relevant secondary care trust DTCs and approved by the Nottinghamshire APC.
    *Specialist is defined by the APC as a clinician who has undertaken an appropriate formal qualification or recognised training programme within the described area of practice
      

    Amber 3

    Primary care/ non specialist may initiate as per APC guideline.
    The supporting prescribing guideline must have been agreed by the relevant secondary care trust D&TC(s) and approved by the Nottinghamshire APC.
      

    Green

    Medicines suitable for routine use within primary care.
    Can be initiated within primary care within their licensed indication, in accordance with nationally recognised formularies, for example the BNF, BNF for Children, Medicines for Children or Palliative Care Formulary. Primary care prescribers take full responsibility for prescribing.   

    OTC

      

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